QUINOLINIC ACID

PRODUCT IDENTIFICATION

CAS NO. 89-00-9

QUINOLINIC ACID

EINECS NO. 201-874-8
FORMULA (C5H3N)(COOH)2
MOL WT. 167.12

H.S. CODE

 

TOXICITY

 
SYNONYMS 2,3-Pyridinedicarboxylic acid; Acide pyridine-2,3-dicarboxylique;
Pyridine-2,3-dicarboxylate; Pyridine-2,3-dicarboxylic acid; ácido piridina-2,3-dicarboxílico;
SMILES

 

CLASSIFICATION

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE white crystalline powder
MELTING POINT 182 - 185 C (Decomposes)
BOILING POINT  
SPECIFIC GRAVITY  
SOLUBILITY IN WATER Insoluble
pH  
VAPOR DENSITY  

AUTOIGNITION

 

NFPA RATINGS

 

REFRACTIVE INDEX

 

FLASH POINT

 

STABILITY Stable under ordinary conditions

GENERAL DESCRIPTION AND APPLICATIONS

Pyridinecarboxylic acids are active in the metabolism of body. For example, nicotinic acid (3-pyridinecarboxylic acid) is is a constituent of the redox coenzymes nicotinamide adenine dinucleotide and nicotinamide adenine dinucleotide phosphate which are essential in energy metabolism in the living cell. Pyridinecarboxylic acids act as chelating agents of elements such as chromium, zinc, manganese, copper, iron, and molybdenum in the body. They are involved in phenylalanine, tryptophan, and alkaloids production, and for the quantitative detection of calcium. This forms a complex with zinc, may facilitate the passage of zinc through the gastrointestinal wall and into the circulatory system. Nicotinic acid reacts with hemoglobin and myoglobin,  which provide an application in meat processing to form brighter colour. It acts to reduce plasma cholesterol, as a vasodilator and to treat pellagra.  It is used for the prophylaxis. Pyridinecarboxylic acids  and their derivatives can be studied for these effects. They used as intermediate to produce pharmaceuticals and metal salts for the application of nutritional supplements. Quinolinic acid inhibits glucose synthesis. Fusaric acid (butyl ester of picolinic acid) inhibits dopamine beta-hydroxylase activity.
  • Nicotinic acid (Niacin; 3-Pyridinecarboxylic acid, CAS #: 59-67-6)
  • Isonicotinic acid (4-Pyridinecarboxylic acid, CAS# : 55-22-1)
  • Picolinic acid (2-Pyridinecarboxylic acid; 98-98-6)
  • Fusaric acid (5-Butyl-2-pyridinecarboxylic acid, 536-69-6)
  • Dinicotinic acid (3,5-Pyridinedicarboxylic acid, 499-81-0)
  • Dipicolinic acid (2,6-Pyridinedicarboxylic acid, 499-83-2)
  • Quinolinic acid (2,3-Pyridinedicarboxylic acid, 89-00-9)
  • Lutidinic acid (2,4-Pyridinedicarboxylic acid, 499-80-9)
  • Cinchomeronic acid (3,4-Pyridinedicarboxylic acid, 490-11-9)
  • Isocinchomeronic acid (2,5-Pyridinedicarboxylic acid, 100-26-5)
SALES SPECIFICATION

APPEARANCE

white crystalline powder
ASSAY

99.0 min

LOSS ON DRYING

1.0% max

MOISTURE 0.1% max
TRANSPORTATION
PACKING
 
HAZARD CLASS  
UN NO.  
OTHER INFORMATION
Hazard Symbols: XI, Risk Phrases:36/37/38, Safety Phrases: 24-36